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Clinical trials that are designed to help inform practice in the real world are known as pragmatic trials. They are usually characterized by a focus on the practical aspects of the study design, including the recruitment process and consent as well as adherence to the use of routinely available equipment.

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A pragmatic study that involves various investigators and participants from diverse geographical locations is the Home Blood Pressure Management study (HBPM). This type of heterogeneity is essential for practical trials to be valid and helps to reduce bias in the results. However, too much heterogeneity can result in problems with the design of the trial.

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Pragmatic Play offers not only mobile-friendly slot machines but also live casino and table games. Pragmatic Play is licensed and is regulated by various regulatory bodies that include the Malta Gaming Authority and UK Gambling Commission. The company's games are secured by top-of-the-line encryption, and its security team is available to help players with any issues.

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Pragmatic Play has earned a reputation for providing top-quality games and an outstanding user experience. Its software is accessible on mobile devices as well as in various languages. It has earned itself the status of one of the top gaming platforms in the casino industry despite its relatively young age. Its latest releases include Wolves, a 5-reel video slot that has a healthy RTP and stunning graphics. Its other notable titles are Wolf Gold and Chilli Heat.

Pragmatic trials aim to mimic real-life settings and achieve maximum external validity. They are typically commissioned by policymakers and practitioners to inform their decisions. They can also be a great method to determine the causal relationship between an intervention and its results. However, 프라그마틱 정품 사이트 they should not be used in lieu for the use of explanation studies.

The pragmatism idea is controversial, and there are doubts about whether pragmatic trials should replace explanatory trials or 슬롯 complement them. Schwartz and Lellouch1 suggested the distinction between explanatory trials, which validate the clinical or physiological hypothesis, and 프라그마틱 정품 pragmatic trials that inform the practice and policy decisions. They also suggested a framework dubbed PRECIS for pragmatic trials.2 This tool attempted to define the traits of a pragmatic research study which includes the recruitment, design, and delivery of the intervention and its follow-up.

There is a growing trend in the number of pragmatic trials that have been published. A recent Medline search using the terms naturalistic and pragmatic, which was limited to randomized controlled trials (RCTs), yielded 34 articles, shown in red in Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatism. It is important to note that the majority of these studies were conducted in primary-care settings.